Sublingual Immunotherapy using The La Crosse Method™ Protocol

Since 1970, Allergy Associates of La Crosse has pioneered allergy treatment using sublingual immunotherapy, or allergy drops taken under the tongue.

We developed the La Crosse Method Protocol as a comprehensive tool to diagnose and precisely treat allergies and related conditions. Our protocol is the most widely used and clinically established published sublingual, or allergy drop immunotherapy protocol in the U.S. It provides a safe, effective alternative to allergy shots and treats the root cause of your allergies.

What makes the Protocol different is our approach, based on more than 50 years of clinical use, international research, and our understanding of the unique mechanism that gives patients a safe, effective way to retrain the immune system so it can tolerate the allergens that once made them sick.

No two patients have the exact same allergies. Our treatment is based on thorough diagnostics and testing,  and targets each patient’s unique “allergic fingerprint” using optimal dosing.

Allergy drop safety

Allergy drop safety

Allergy drop immunotherapy is a safe, low cost treatment that you can take wherever you need to be. Patients need fewer clinic visits than shot immunotherapy – usually only a few rechecks annually after starting therapy versus weekly, bi-weekly, or monthly shot visits.

The treatment’s safety profile allows more people to be candidates, including those with allergies to foods and molds. Personalized allergy drop immunotherapy can help allergy-related health conditions like asthma and eczema (atopic dermatitis). And allergy drops can help more patients including infants, the severely allergic, and others who have given up hope of an effective allergy treatment.

Validation Institute logoLa Crosse Method Protocol outcomes have been validated through the Validation Institute, an independent team of population health scientists and bio-statisticians who provide objective review to validate performance in healthcare. For more information, visit

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Success Stories

Allergy Associates of La Crosse literally changed my life. Before discovering Allergy Associates through a friend, I had a long history of severe and multiple food, drug, and environmental allergies and asthma, which had never been successfully managed by other renowned allergy specialists. My lengthy history includes a medical discharge from the U.S. Air Force,…
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